How Is CBD Used To Treat Alzheimer's?

How Is CBD Used To Treat Alzheimer's?

Dec 5th 2019

Alzheimer’s is a disease that thousands of Americans are dealing with whether they may have early on-set Alzheimer's or have been diagnosed with the disease. While this is not a new disease that we haven’t heard of, research and testing continue for treating the symptoms of Alzheimer’s or even preventing the disease from developing and worsening. Over the years, new research and development have grown for using CBD oil as an alternative to treat Alzheimer’s.

What is CBD?

CBD stands for cannabidiol, which is a compound that is found naturally in hemp plants. CBD is one of the two most common compounds found in the Cannabis or Hemp plant. It is a naturally occurring substance that is used in CBD oils, CBD topicals, or CBD edibles. CBD also interacts with our endocannabinoid system (ECS) which is made up of the CB1 and CB2 receptors. It’s important to understand that CB1 receptors are present in each part of our brain as well as the hippocampus. The hippocampus is responsible for our learning and memory functions. While CB2 receptors are present in particular immune cells in our brain which is known as microglia. 

What is Alzheimer’s Disease?

Alzheimer’s disease is a form of dementia that can cause problems such as memory loss, cognitive thinking, and behavior. Symptoms typically develop slowly and get worse over a period of time, resulting in a difficulty to complete regular daily tasks.

Currently, researchers aren’t exactly on the same page with what is the cause of the disease. However, scientists have classified two proteins, Beta-Amyloid and Tau, that play a vital role in the progression of the disease.

Today, many of the treatments for Alzheimer’s are used to manage symptoms. However, they come with a laundry list of side effects such as nausea, vomiting, loss of appetite, headache, dizziness, muscle weakness, and more. Some long term side effects can also include a reduced heartbeat, yellowing of the skin, tingling of the distal extremities, stroke, and liver failure just to name a few.

For people battling this disease, these symptoms from the medication might seem like they are worth the risk. However, many are turning to alternative options such as using CBD oil to help treat their Alzhermier's. 

How Can CBD Help Treat Alzheimer’s?

Cannabinoids work in our bodies at a cellular level. According to a study conducted by Frontiers in Pharmacology, they have the ability to remove the buildup of senile plaques and to prevent inflammation which is one of the biggest accelerations in the progression of Alzheimer’s.

CBD Can Reduce Inflammation

Inflammation in the brain is one of the main results in a person that is diagnosed with Alzheimer’s. According to the Alzheimer's Drug Discovery Foundation, “Like most things in biology, the answer is complicated, but more and more research suggests that inflammation plays a very active and early role in the development of Alzheimer’s.” 

Studies have shown that CBD may help reduce inflammation and is able to do so by engaging with receptors in the body. One of the main benefits of CBD is promoting homeostasis in the body which results in this reduction of inflammation. Where there is inflammation in the body, CBD will aid to regulate this. 

CBD Inhibits the Formation of Neurofibrillary Tangles

According to the Laboratory of Pathology and Electron Microscopy, “The neuropathological diagnosis of Alzheimer's disease relies on the presence of both neurofibrillary tangles and senile plaques. The number of neurofibrillary tangles is tightly linked to the degree of dementia, suggesting that the formation of neurofibrillary tangles more directly correlates with neuronal dysfunction.” Neurofibrillary tangles are formed by hyperphosphorylation of a microtubule protein that is known as tau which creates an aggregate group of this protein in an insoluble form and these are common indicators of the Alzheimer's disease. 

Incorporating CBD (cannabidiol) into our bodies helps the brain to heal and repair itself. According to a study, CBD triggers the activation of CB receptors of the endocannabinoid system which affects the Tao phosphorylation. This study concluded that when the CB1 and CB2 receptors were activated by CBD it was evident that the tau protein hyperphosphorylation was drastically reduced, which as a result reduced the formation of neurofibrillary tangles. 

Overall, if you or someone you know is battling with this disease we always recommend that you consult with your primary doctor about the CBD benefits and what it can do for you. Whether you want to buy CBD oil for pain or CBD oil for inflammation you can buy CBD oil with Doc Patels. Doc Patels CBD oil is all Curated By Doctors ensuring that ourpure CBD oil is consistent and safe to use. You can browse through our 0.00% THC Broad Spectrum CBD Oil here to choose the right flavor and dosage.

Sources:

Alzheimers's Drug Discovery Foundation

Laboratory of Pathology and Electron Microscopy

Wikipedia

Frontiers in Pharmacology

National Institute On Aging